Clinical research has shown that removing potentially detrimental peritoneal fluid and achieving primary fascial closure are important goals when managing patients who require an open abdomen for the treatment of critical illness.4
The method of temporary abdominal closure chosen may play an important role in patient outcomes2,5,6
In the twenty-center observational prospective study comparing ABTHERA™ Therapy to Barker’s vacuum-packing technique in trauma and surgical patients, ABTHERA™ Open Abdomen Negative Pressure Therapy was associated with a significantly improved 30-day primary fascial closure rate, and a 30-day all cause mortality rate (p=0.03 and 0.01 respectively).2
Explore Products for Open Abdomen Management
Active Abdominal Therapy
The ABTHERA™ Open Abdomen Negative Pressure Therapy (NPT) System is indicated for temporary bridging of abdominal wall openings where primary closure is not possible and/or repeated abdominal entries are necessary. The intended use of this system is for use in open abdominal wounds, with exposed viscera, including but not limited to abdominal compartment syndrome.
1. Miller PR, Meredith JW, Johnson JC, Chang MC. Prospective evaluation of vacuum-assisted fascial closure after open abdomen: planned ventral hernia rate is substantially reduced. Annals of Surgery. 2004 May;239(5):608-614.
2. Cheatham ML, Demetriades D, Fabian TC, et al. Study Examining Clinical Outcomes Associated with a Negative Pressure Wound Therapy System and Barker’s Vacuum Packing Technique. World Journal of Surgery. 2013 September; 37(9):2018-2030.
3. Kirkpatrick AW, Roberts DJ, Faris PD, et. al. Active Negative Pressure Peritoneal Therapy After Abbreviated Laparotomy: The Intraperitoneal Vacuum Randomized Controlled Trial. Annals of Surgery. 2015 July: 262(1):38-46
4. Cheatham ML, Safcsak K. Is the evolving management of intra-abdominal hypertension and abdominal compartment syndrome improving survival? Crit Care Med 2010;38:402-407.
5. Kaplan M, Banwell P, Orgill DP, et al. Guidelines for the Management of the Open Abdomen. Wounds. 2005 Oct;17(Suppl 1):S1 S24.
6. Cheatham ML, et al. Abdominal perfusion pressure; a superior parameter in the assessment of intra-abdominal hypertension. Journal of Trauma. 2000 Oct:49:621-626.
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