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PROMOGRAN PRISMA™ Matrix


PROMOGRAN PRISMA™ Matrix
PROMOGRAN PRISMA™ Matrix

A Clinically Proven Combination

PROMOGRAN PRISMA™ Matrix is comprised of a sterile, freeze dried composite of 44% oxidized regenerated cellulose (ORC), 55% collagen and 1% silver-ORC. Silver-ORC contains 25 % w/w ionically bound silver, a well-known antimicrobial agent.

Optimum wound environment
PROMOGRAN PRISMA™ Matrix maintains a physiologically moist microenvironment at the wound surface. This environment is conducive to granulation tissue formation, epithelization and optimal wound healing. Ionically-bound silver is an antimicrobial agent.
 
Clinically Proven
The efficacy of PROMOGRAN PRISMA™ Matrix is supported by a body of clinical evidence, including 1 published RCT1.
 

Overview

Supports Granulation and Epitheliazation

In a 14-week RCT comparing PROMOGRAN PRISMA™ Matrix (n=25), with Control (n=15), the number of patients withdrawn from the study due to infection was Significantly greater in the control group 0% VS. 31% (p=0.012)1 (n=40)

Significantly Greater Rate of Wound Healing At Week Four

79% VS. 43% For the standard of care (Improved defined as >50% reduction in wound size)1

Economic Value

With PROMOGRAN™ Matrix Wound Dressing and PROMOGRAN PRISMA™ Matrix. 

System Components & Accessories

How it Works

  • About
  • Specifications
  • Materials For Download

About

Maintains an optimum wound-healing environment

In the presence of exudate, PROMOGRAN PRISMA™ Matrix transforms into a soft, conformable, biodegradable gel, allowing contact with all areas of the wound.

PROMOGRAN PRISMA™ Matrix maintains a physiologically moist microenvironment at the wound surface. This environment is conducive to granulation tissue formation, epithelialization and optimal wound healing.
  • Optimum wound environment
  • Clinically proven
 
PROMOGRAN PRISMA™ Matrix How Does It Work
PROMOGRAN PRISMA™ Matrix How Does It Work

Specifications

Product description
PROMOGRAN PRISMA™ Matrix is comprised of a sterile, freeze dried composite of 44% oxidized regenerated cellulose (ORC), 55% collagen and 1% silver-ORC.
Silver-ORC contains 25 % w/w ionically bound silver, a well-known antimicrobial agent. In the presence of exudate, the PROMOGRAN PRISMA™ Matrix transforms into a soft, conformable, biodegradable gel, and thus allows contact with all areas of the wound.
 
PROMOGRAN PRISMA™ Matrix, when covered with a semi-occlusive dressing, maintains a physiologically moist microenvironment at the wound surface.
This environment is conducive to granulation tissue formation, epithelialization and optimal wound healing.
 
PROMOGRAN PRISMA™ Matrix provides an effective antibacterial barrier as demonstrated by the in-vitro reduction of bacterial growth with common wound pathogens such as, Pseudomonas aeruginosa, Staphylococcus aureus, Eschericia coli and Streptococcus pyogenes. Reduction of bacterial bioburden in the dressing may result in reduced risk of infection. Literature reports of in-vitro testing indicate that collagen fibers provide a biodegradable matrix for cellular invasion and capillary growth. In laboratory testing, Collagen-ORC has been shown to absorb components of wound exudate.

Indications & Applications

Indications & Applications

  • Indications
  • Applications

Indications for Use

PROMOGRAN PRISMA™ Matrix is intended for the management of exuding wounds. Under the supervision of a health care professional, PROMOGRAN PRISMA™ Matrix may be used for the management of:
  • Diabetic ulcers
  • Venous ulcers
  • Pressure ulcers
  • Ulcers caused by mixed vascular etiologies
  • Full-thickness & partial thickness wounds
  • Donor sites and other bleeding surface wounds
  • Abrasions
  • Traumatic wounds healing by secondary intention
  • Dehisced surgical wounds
 
PROMOGRAN PRISMA™ Matrix is a primary dressing that can be cut to fit wound with scissors and used in combination with either a semi-occlusive or non-occlusive secondary dressing. Prior to application in dry wounds saline solution should be used to hydrate PROMOGRAN PRISMA™ Matrix
 
Before use, physicians should review complete risk information and essential prescribing information which can be found in the Instructions for Use.
 

Applications

Place How to Apply PROMOGRAN PRISMA Video here
 
Storage
PROMOGRAN PRISMA™ Matrix should be stored away from direct light. Over-exposure to light may cause some discolouration, however this does not affect the release of silver from the dressing. Store below 25 °C / 77 °F. Prepare wound bed per your standard wound care protocol and debride when necessary. For optimal effect, apply PROMOGRAN PRISMA™ Matrix directly to the whole wound bed.
  • For a wound with low or no exudate apply PROMOGRAN PRISMA™ Matrix and hydrate with saline solution. This will initiate the transformation of the PROMOGRAN PRISMA™ Matrix into a gel.
  • After hydration, through exposure to wound exudate or saline, the PROMOGRAN PRISMA™ Matrix gel will intimately come into contact with the wound surface.
  • The biodegradable PROMOGRAN PRISMA™ Matrix gel is naturally absorbed into the body over time.
  • In order to maintain a moist wound healing environment PROMOGRAN PRISMA™ Matrix must be covered with a semi-occlusive dressing (e.g. BIOCLUSIVE™ Plus Transparent Film Dressing, TIELLE™ Hydropolymer Adhesive Dressing or TIELLE™ Plus Hydropolymer Adhesive Dressing) or a non-occlusive secondary dressing and fixed to the skin with a non-irritating tape.
  • After initial application, reapply PROMOGRAN PRISMA™ Matrix to the wound daily or per physician recommendation. It is not necessary to remove any residual PROMOGRAN PRISMA™ Matrix during dressing changes.
 
Do not use if package is damaged.
The use by date of this product is printed on the packaging.
Do not resterilize.
 
Caution: Federal Law (USA) restricts this device to sale by or on the order of a properly licensed healthcare practitioner. This caution is not applicable outside the U.S.
 

Evidence & Outcomes

The efficacy of PROMOGRAN PRISMA™ Matrix is supported by clinical evidence, including a published RCT. Acelity Clinical Evidence is a resource for healthcare professionals to explore preclinical, clinical, and review articles discussing the use of KCI and Systagenix products. Use our powerful search tool to customize your view of the Acelity product evidence.

For questions or to request published literature contact Medical Information

Clinical Evidence

Additional summary of evidence and outcomes.

Evidence & Outcomes

Evidence & Outcomes

Title Study Type Date Authors