PROMOGRAN PRISMA™ Matrix is comprised of a sterile, freeze dried composite of 44% oxidized regenerated cellulose (ORC), 55% collagen and 1% silver-ORC.
Silver-ORC contains 25 % w/w ionically bound silver, a well-known antimicrobial agent. In the presence of exudate, the PROMOGRAN PRISMA™ Matrix transforms into a soft, conformable, biodegradable gel, and thus allows contact with all areas of the wound.
PROMOGRAN PRISMA™ Matrix, when covered with a semi-occlusive dressing, maintains a physiologically moist microenvironment at the wound surface.
This environment is conducive to granulation tissue formation, epithelialization and optimal wound healing.
PROMOGRAN PRISMA™ Matrix provides an effective antibacterial barrier as demonstrated by the in-vitro reduction of bacterial growth with common wound pathogens such as, Pseudomonas aeruginosa, Staphylococcus aureus, Eschericia coli and Streptococcus pyogenes. Reduction of bacterial bioburden in the dressing may result in reduced risk of infection. Literature reports of in-vitro testing indicate that collagen fibers provide a biodegradable matrix for cellular invasion and capillary growth. In laboratory testing, Collagen-ORC has been shown to absorb components of wound exudate.